2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7143R
    Monobutyl phthalate (Standard)
    Monobutyl phthalate (Standard) is the analytical standard of Monobutyl phthalate. This product is intended for research and analytical applications. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant.
    Monobutyl phthalate (Standard)
  • HY-122317
    Menthol glucuronide
    Menthol glucuronide, a metabolite of Menthol (HY-N1369), is a plasma and urine biomarker of acute Menthol inhalation.
    Menthol glucuronide
  • HY-12767S
    4-Hydroxyphenyl Carvedilol-d5
    4-Hydroxyphenyl Carvedilol-d5 is the deuterium labeled 4-Hydroxyphenyl Carvedilol.
    4-Hydroxyphenyl Carvedilol-d<sub>5</sub>
  • HY-151930S1
    8′-Hydroxy ABA-d2
    8′-Hydroxy ABA-d2 is the deuterium labeled 8’-Hydroxy ABA[1].
    8′-Hydroxy ABA-d<sub>2</sub>
  • HY-143961S
    Givinostat impurity 5-d4
    Givinostat impurity 5-d4 is the deuterium labeled Givinostat impurity 5[1].
    Givinostat impurity 5-d<sub>4</sub>
  • HY-143977S
    Loxapine impurity 3-d8 iodide
    Loxapine impurity 3-d8 (iodide) is the deuterium labeled Loxapine impurity 3 iodide[1].
    Loxapine impurity 3-d<sub>8</sub> iodide
  • HY-131269
    Febuxostat impurity 7
    		98.18%
    Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.
    Febuxostat impurity 7
  • HY-135388
    ent-Ezetimibe
    ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
    ent-Ezetimibe
  • HY-135372
    Descarbamoyl cefuroxime
    Descarbamoyl cefuroxime is a degradation product of Cefuroxime. Descarbamoyl cefuroxime is also an intermediate for the synthesis of Cephalosporin antibiotics.
    Descarbamoyl cefuroxime
  • HY-G0003S1
    Iloperidone metabolite Hydroxy Iloperidone-d3
    Iloperidone metabolite Hydroxy Iloperidone-d3 is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].
    Iloperidone metabolite Hydroxy Iloperidone-d<sub>3</sub>
  • HY-136591R
    Demoxepam (Standard)
    Demoxepam (Standard) is the analytical standard of Demoxepam. This product is intended for research and analytical applications. Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam exhibits cytotoxicity activity against cancer cell lines. Demoxepam has anticonvulsant and anxiolytic effects.
    Demoxepam (Standard)
  • HY-121899
    1-Oxo Ibuprofen
    1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    1-Oxo Ibuprofen
  • HY-B0794S
    AZ7550-d5
    AZ7550-d5 is the deuterium labeled AZ7550 (HY-B0794). AZ7550, an active metabolite of Osimtinib (AZD9291; HY-15772), inhibits the activity of IGF1R with an IC50 of 1.6 μM[1][2].
    AZ7550-d<sub>5</sub>
  • HY-123144
    N-Hydroxymethylsorafenib
    N-Hydroxymethylsorafenib is a Sorafenib (HY-10201) metabolite, and can be used for research of metabolite of Sorafenib.
    N-Hydroxymethylsorafenib
  • HY-N0873A
    Iso-Sagittatoside A
    Iso-Sagittatoside A is the metabolite of effective Erxian Decoction (EXD, a Chinese medicine prescription for menopausal syndromes) in rat plasma.
    Iso-Sagittatoside A
  • HY-143975S
    Loxapine impurity 2-d8
    Loxapine impurity 2-d8 is the deuterium labeled Loxapine impurity 2[1].
    Loxapine impurity 2-d<sub>8</sub>
  • HY-143964S
    Irbesartan impurity 14-d4
    Irbesartan impurity 14-d4 is the deuterium labeled Irbesartan impurity 14[1]. Irbesartan impurity 14-d4 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Irbesartan impurity 14-d<sub>4</sub>
  • HY-131273
    Febuxostat amide impurity
    Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM
    Febuxostat amide impurity
  • HY-136346S
    Ortho-hydroxy atorvastatin lactone-d5
    Ortho-hydroxy atorvastatin lactone-d5 is deuterium labeled 2-Hydroxy atorvastatin lactone. 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].
    Ortho-hydroxy atorvastatin lactone-d<sub>5</sub>
  • HY-N11886
    5-NH2-Baicalein
    5-NH2-Baicalein is an aminated metabolite of Baicalein (HY-N0196). 5-NH2-Baicalein can be used for research of ammonia and ammonia-associated chronic diseases.
    5-NH2-Baicalein
Cat. No. Product Name / Synonyms Application Reactivity